Palladium-Catalyzed/Norbornene-Mediated <i>ortho</i>-Amination/<i>N</i>‑Tosylhydrazone Insertion Reaction: An Approach to the Synthesis of <i>ortho</i>-Aminated Vinylarenes

Abstract

<i>ortho</i>-Aminated vinylarene derivatives were obtained via a reaction of aryl iodides, <i>N</i>-benzoyloxyamines, and <i>N</i>-tosylhydrazones. This approach involves a palladium-catalyzed, norbornene-mediated <i>ortho</i>-amination/<i>N</i>-tosylhydrazone insertion reaction. In this transformation, one C–N bond and one C–C bond are formed and an amine group is introduced at the <i>ortho</i> position successfully