Scatterplots showing the observed significant correlations between fractional anisotropy (FA) of the three deep grey matter structures of interest and other variables of clinical relevance.
<p>Caudate FA showed a positive correlation with the Expanded Disability Status Scale (EDSS), Ambulation Index and depressive symptomatology as measured by the Center for Epidemiologic Studies Depression scale (CES-D). Putamen FA showed a positive correlation with White Matter (WM) Lesion Volume, as well as an inverse correlation with the Brief Visuospatial Memory Test-Revised (BVMT-R) Total Recall and Delayed Free Recall scores. Thalamus FA showed an inverse correlation with the Symbol Digit Modalities Test (SDMT) and the California Verbal Learning Test-II (CVLT-II) Total Learning scores, as well as a positive correlation with the CES-D score.</p