Stereoselective Synthesis of <i>cis</i>-2-Fluorocyclopropanecarboxylic Acid

Abstract

A rhodium-catalyzed cyclopropanation of 1-fluoro-1-(phenylsulfonyl)­ethylene and diazo esters is described as an effective method for the stereoselective synthesis of <i>cis</i>-2-fluorocyclopropanecarboxylic acid. This process provides an example of the cyclopropanation of electron-deficient olefin and diazoacetates