Lewis Acid
Triggered Reactivity of a Lewis Base Stabilized
Scandium-Terminal Imido Complex: C–H Bond Activation, Cycloaddition,
and Dehydrofluorination
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Abstract
A stable scandium-terminal
imido complex is activated by borane
to form an unsaturated terminal imido complex by removing the coordinated
Lewis base, 4-(dimethylamino)pyridine, from the metal center.
The ensuing terminal imido intermediate can exist as a THF adduct
and/or undergo cycloaddition reaction with an internal alkyne, C–H
activation of a terminal alkene, and dehydrofluorination of fluoro-substituted
benzenes or alkanes at room temperature. DFT investigations further
highlight the ease of C–H activation for terminal alkene and
fluoroarene. They also shed light on the mechanistic aspects
of these two reactions