Dose-response curves and susceptibility distributions inferred from mortality measurements 30 and 50 days post-challenge.

Abstract

<p>Dose-responses models adopted here are the standard formulations (1–3). A,D, Curves represent the fitted dose-response model to mortality on selected day post-challenge (dots), for Wolb⁻ (black) and Wolb⁺ (blue). Shaded areas represent the 95% CI. B,E, Distribution of susceptibility to infection in Wolb⁺. The posterior median distribution is the curve and the shaded area is the 95% CI. C,F, Posterior samples of the Beta-distribution shape parameters describing Wolb⁺ susceptibility in blue. Red dot mark the median of the respective distributions. The homogeneous model was adopted for Wolb⁻.</p