<p>Numbers represent Log<sub>10</sub> genome copy numbers (GCN)/mg of tissue. Bold numbers indicate that samples were positive for both FMDV RNA (qRT-PCR) and virus isolation, (+) indicates that virus isolation was positive but FMDV RNA content was below the limit of detection, (-) indicates double negative samples. Limit of detection: 2.52 Log<sub>10</sub> GCN/mg of tissue.</p><p>* Visceral organs included liver, spleen, kidney, pancreas, ileum and Peyer's patches. Other tissues analyzed with consistently negative results were epiglottis, larynx, pharyngeal-diverticulum, salivary glands, adrenal glands, bone marrow.</p><p>Tissue distribution of FMDV during the pre-viremic phase of infection following IOP inoculation.</p