Iron-Catalyzed Cascade Carbochloromethylation of Activated
Alkenes: Highly Efficient Access to Chloro-Containing Oxindoles
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Abstract
An iron-catalyzed
carbodi- and trichloromethylation of activated
alkenes with readily available dichloro- and tetrachloromethane has
been developed. A diaryliodonium salt is used as an efficient oxidant
in this transformation. This reaction tolerates a variety of functional
groups and allows for a highly efficient synthesis of various chloro-containing
oxindoles