NGS coverage maps for <i>E. coli</i> from input (A) and bound (B) fractions of the synthetic mixture.

Abstract

<p>Reads were mapped to <i>E. coli</i> O157:H7 EDL933 and binned into 1000 bp bins. (A) The average depth of coverage is 0.5 for <i>E. coli</i> in the input fraction (green), with 62% of the genome covered. (B) For the bound fraction (blue), the average depth of coverage increases to 60 and 99.5% of the genome is covered. The input fraction (green) is also plotted here for comparison to the bound fraction at the same scale.</p