<p>Table shows the percentage of HCNEs that were positive for any of the six analyzed histone modification markers or CBP binding across 12 developmental stages. A dash (β) indicates missing data. An HCNE is considered to have a given marker when at least 10% of its length overlapped with the marker. We observed a prominent presence of H3K27me3 and H3K9me3 among the HCNEs throughout development. Markers associated with the active chromatin state (H3K27ac, H3K9ac, and H3K4me3) displayed stage-specific patterns.</p><p>Dynamic histone modification at HCNEs during <i>Drosophila</i> development.</p