<p>Acute CCl<sub>4</sub>-induced injury in <i>Rgs5<sup>+/+</sup></i> mice (<b>A–C</b>) and <i>Rgs5<sup>LacZ/LacZ</sup></i> (<b>D–F</b>). <b>A,D</b>. Uninjured mice are histologically normal. <b>B</b>,<b>E</b> At 48 hr post CCl<sub>4</sub> injection, foci of necrosis are visible central veins in both <i>Rgs5<sup>+/+</sup></i> and <i>Rgs5<sup>LacZ/LacZ</sup></i> mice. <b>C,F</b>. At 96 hr post injury, clearance of necrotic hepatocytes is underway and infiltrating cells remain at the site of injury. <b>F</b>. In <i>Rgs5<sup>LacZ/LacZ</sup></i> mice, hepatocytes throughout the liver have cleared cytoplasm. Scale bars are 100 µm.</p
