Abstract

<p>Cell counts in BAL fluid collected from unchallenged mice (naïve) and 6 h after direct airway exposure to LPS, with i.p. NTM peptide (cSN50.1) or diluent control (saline) treatment. The LPS-induced increase in total cells is comprised primarily of neutrophils. Neutrophil trafficking to BAL is significantly reduced by NTM treatment while monocytes/macrophages and lymphocytes are not affected. Data are presented as mean ± standard error, <i>n</i> = 4 naïve and 5–7 NTM- or saline-treated animals/group from two independent experiments. *<i>p</i><0.05, **<i>p</i><0.005 by Mann-Whitney <i>U</i> test comparing LPS-challenged groups.</p

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