Molecular Signaling Network of Cripto-1

Abstract

<p>This is a presentation on identification of an incoherent feed-forward loop in Cripto-1 signaling. Cripto-1 is an oncofetal protein. We have shown that Cripto-1 can activate both PI3K pathway as well increases PTEN. This creats a self-regulatory feedforward loop. This presentation is based on the paper: Cancer Lett. 2012 318(2): 189-98 [PMID: 22182448]. This presentation was made at a meeting at B. Borooah Cancer Institute (BBCI), Guwahati, India in 2012</p

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