<p>WT and d/d mice received 2×10<sup>5</sup> CFU of <i>P. aeruginosa</i> PA011 intranasally, and WT mice treated with NaCl 0.9% were used as control. Body weight variation 20 h after infection is shown in (A). Myeloperoxidase activity was quantified (B) and absolute numbers of cells; (macrophages and neutrophils) were measured in BALF (C). Bacterial load (total CFU) was determined in BALF and in lung homogenate (D). Total protein concentration was evaluated in BALF (E) and KC (F), IL-1β (G) and TNF-α (H) were measured in lung homogenate. Cell infiltration was observed on H&E stained slide (I) and scored (J). (n = 5–6) Values are in mean +/− SEM; * for p<0.05; ** for p<0.01 and *** for p<0.001. ns for non-significant.</p
