<div><p>Leaves of <i>Sorbus</i> L. have been used in various traditional medicine systems. Phenolic compounds determine the main pharmacological effects of <i>Sorbus</i> L. In this study, phytochemical and antioxidant profiles of <i>Sorbus anglica</i>, <i>Sorbus aria</i>, <i>Sorbus arranensis</i>, <i>Sorbus aucuparia</i>, <i>Sorbus austriaca</i>, <i>Sorbus caucasica</i>, <i>Sorbus commixta</i>, <i>Sorbus discolor</i>, <i>Sorbus gracilis</i>, <i>Sorbus hostii</i>, <i>Sorbus semi-incisa</i> and <i>Sorbus tianschanica</i> were determined. Twenty four constituents were identified in <i>Sorbus</i> L. species using ultra high performance liquid chromatography coupled to quadruple and time-of-flight mass spectrometers. Post-column FRAP assay identified compounds with reducing activity and revealed significantly greatest total antioxidant activity of 175.30 μmol TE/g DW, 169.20 μmol TE/g DW and 148.11 μmol TE/g DW in <i>S. commixta</i>, <i>S. discolor</i> and <i>S. gracilis</i> leaf samples, respectively, with neochlorogenic and chlorogenic acids being most significant contributors. Characteristic fingerprints of phytochemical and antioxidant profiles could be applied for the quality evaluation of various raw materials of <i>Sorbus</i> L. species.</p></div