Synthesis and Characterization of N<i>-</i>Donor-Functionalized Enantiomerically Pure Pentadienyl Ligands Derived
from (1<i>R</i>)‑(−)-Myrtenal
- Publication date
- Publisher
Abstract
A series of enantiomerically pure
−SiMe<sub>2</sub>NR<sub>2</sub> (R = Me, Et) substituted pentadienyl
ligands were prepared
starting from the natural product (1<i>R</i>)-(−)-myrtenal.
Deprotonation with a Schlosser superbase yields the corresponding
potassium salts, which were characterized by various spectroscopic
techniques. In solution these neutral N-donor-substituted pentadienyl
systems predominantly adopt a <i>U</i> conformation, but
in two cases the rare <i>S</i> conformation was also observed
as a minor component in solution. Addition of 18-crown-6 allowed the
molecular structures of two of these potassium pentadienyls to be
determined by X-ray diffraction. Interestingly, η<sup>5</sup> and κ<i>N</i> coordination of the pentadienyl system
to the [K(18-crown-6)]<sup>+</sup> cation was observed. Furthermore,
these ligand systems also coordinate to transition metals and form
an open titanocene, open vanadocenes, open chromocenes, and half-open
trozircenes with [TiCl<sub>3</sub>(thf)<sub>3</sub>], [VCl<sub>3</sub>(thf)<sub>3</sub>], CrCl<sub>2</sub>, and [(η<sup>7</sup>-C<sub>7</sub>H<sub>7</sub>)ZrCl(tmeda)], respectively. These complexes
were characterized by elemental analyses and various spectroscopic
techniques. However, no coordination of the pendant −SiMe<sub>2</sub>NR<sub>2</sub> group to the metal centers was observed. In
addition, significant steric crowding in these open metallocenes prevents
the formation of isolable CO or PMe<sub>3</sub> adducts. This was
further corroborated by EPR studies on an open vandadocene, which
showed that no adduct formation occurs at ambient temperature in solution,
but a weak PMe<sub>3</sub> adduct was detected at 26 K