<p>Nasal swabs are represented by black dots, throat swabs by red dots, sputum samples by green dots. (A) Principal Component Analysis of samples obtained from clinically stable children with CF. In panel (B) samples from patients during exacerbation were added. Pearson correlations were performed to highlight which OTUs were responsible for the divergence among the samples. Correlation was considered significant when the coefficient of correlation was higher than 0.6 and p-value < 0.01. (C) Principal Coordinates Analysis was performed on samples obtained from clinically stable CF patients or (D) on all available samples from CF patients irrespective of the clinical status.</p
