Fe-Catalyzed Double Cross-Dehydrogenative Coupling
of 1,3-Dicarbonyl Compounds and Arylmethanes
- Publication date
- Publisher
Abstract
Fe-catalyzed tandem cross-dehydrogenative
coupling of the methyl
group in arylmethanes with 1,3-dicarbonyl compounds has been developed.
The reaction affords one new C(sp<sup>3</sup>)–C(sp<sup>2</sup>) bond and one new C(sp<sup>3</sup>)–C(sp<sup>3</sup>) bond
in a one-pot protocol. Further study suggests that this reaction might
start with a Friedel–Crafts-type reaction (cross-dehydrogenative
arylation) followed by cross-dehydrogenative coupling with an activated
methylene group under mild oxidative conditions
