Ubiquitous Assembly of Amphiphilic Baskets into Unilamellar
Vesicles and Their Recognition Characteristics
- Publication date
- Publisher
Abstract
An
amphiphilic basket of type <b>1</b> (339 Å<sup>3</sup>)
has been found to assemble into unilamellar vesicles in water.
The assembled host encapsulates organophosphonates (OPs) (119–185
A<sup>3</sup>) with a particularly high affinity (<i>K</i><sub>a</sub> ∼ 10<sup>5</sup> M<sup>–1</sup>) toward
dimethyl phenylphosphonate (185 Å<sup>3</sup>) whose size and
shape resemble that of soman (186 Å<sup>3</sup>). Importantly,
the entrapment of OPs prompts a phase transformation of vesicular <b>1</b> into nanoparticles or larger vesicles as a function of the
shape of the host–guest complex