Graphical representation of the TOOL meta-module.

Abstract

<p>Nodes of the unweighted network (TOM > 0.1) are visualized as circles and correlations between nodes as lines (edges). Node size is proportional to degree of unweighted connectivity; the colors of the edge of the nodes correspond to module membership; edge width and opacity are proportional to TOM and adjacency values between the two connected nodes, respectively. The central color of each node is based on the mean expression log<sub>2</sub> fold-change (up-regulation in red, down-regulation in blue) in response to necrotrophs (left) and biotrophs (right). The shape of the network is based on a force-directed graph calculation which creates a shape based on centrality computed with Cytoscape v. 2.8 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0118731#pone.0118731.ref029" target="_blank">29</a>]. Intra-modular hub genes are numbered according to their ranked unweighted connectivity.</p

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