Cs<sub>2</sub>CO<sub>3</sub>‑Promoted Carboxylation
of <i>N</i>‑Tosylhydrazones with Carbon Dioxide toward
α‑Arylacrylic Acids
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Abstract
A Cs<sub>2</sub>CO<sub>3</sub>-promoted carboxylation of <i>N</i>-tosylhydrazones and CO<sub>2</sub> has been developed.
The reaction proceeded efficiently at 80 °C under atmospheric
CO<sub>2</sub>, gave the corresponding α-arylacrylic acids in
moderate to good yields. This method was featured with (1) the employment
of Cs<sub>2</sub>CO<sub>3</sub> rather than <sup><i>n</i></sup>BuLi as the base; (2) a reaction temperature of 80 °C
rather than −78 °C
