<p>The dehydrogenases directly involved on mitochondrial electron transfer from nutrient oxidation to respiration are depicted in their respective colors utilized throughout this work, as following: complex I (light green), ProDH (dark green), G3PDH (red) and ETF:QOR (blue). The contribution of dehydrogenases to respiration are represented by their boxes, fonts, and lines sizes. Electron leak and O<sub>2</sub><sup>•¯</sup> formation induced by different substrates are represented by steam clouds, obeying the same color and size pattern described for dehydrogenases. Noteworthy, the steam cloud location in this scheme does not represent the exact site of O<sub>2</sub><sup>•¯</sup> production, since we were unable to precisely define these sites in this work. CACT, carnitine-acylcarnitine transferase; CPT2, carnitinepalmitoyl transferase 2; palm-CoA, palmitoyl-CoA; αKG, alpha-ketoglutarate; Δ1PC, Δ-1-pyrroline-5-carboxylate; DHAP, dihydroxyacetone phosphate; PDH, pyruvate dehydrogenase; IMS, intermembrane space; MM, mitochondrial matrix.</p
