Selective (Bio)Functionalization of Solid-State Nanopores

Abstract

We present a method to selectively (bio)­functionalize nanoscale features with the same materials chemistry. It was successfully combined with nanosphere lithography to fabricate and functionalize solid-state nanopores with PEG-brushes, supported lipid membranes, and functional proteins over large areas. The method is inexpensive, can be performed without specialized equipment, and can be applied to both topographic and planar surface modification

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