Phase Transfer Reagent Promoted Tandem Ring-Opening
and Ring-Closing Reactions of Unique 3‑(1-Alkynyl) Chromones
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Abstract
A phase
transfer reagent promoted tandem ring-opening and ring-closing
reaction of 3-(1-alkynyl) chromones has been developed. This process
remarkably generates functionalized 3-acyl-2-substituted chromones.
Interestingly, when 3-(hepta-1,6-diyn-1-yl)chromone derivatives are
applied, a novel tetracyclic chromone scaffold can be obtained by
a further intramolecular 4 + 2 cyclization