Development and Application
of α‑Heteroatom
Ketones in Asymmetric Michael Reaction with β-<i>trans</i>-Nitroalkenes
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Abstract
The successful design and application
of a new type of <i>N</i>-phenyl-imidazole-modified α-heteroatom
ketones in
asymmetric <i>anti</i>-selective Michael reactions with
β-<i>trans</i>-nitroalkenes is reported. High yields
and enantioselectivities could be obtained, and the corresponding
conjugate adducts could be further transformed into related chiral
esters and cyclopropane derivatives with excellent enantioselectivities
