Domino
Aryne Precursor: Efficient Construction of
2,4-Disubstituted Benzothiazoles
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Abstract
An
aryne precursor with a potential to perform domino aryne chemistry
was proposed and synthesized. The reaction of this reagent with benzothioamide
derivatives could afford 2,4-disubstituted benzothiazole with sequential
incorporation of C–S, C–N, and C–C bonds on the
consecutive three positions of the aryne precursor