Abstract

<p>(<b>A, B</b>) mRNA or protein was isolated from WT retinas at the indicated time points after ONC. (<b>A</b>) Results are the fold expression of the shared proteasome subunit α7 or immunoproteasome subunits lmp2 (β1i), mecl-1 (β2i), and lmp7 (β5i), and are the mean ± S.E. of 3–5** mice/group compared to control (day 0). (*, p≤0.05 by one-way ANOVA with Dunnett’s post-test compared to the ‘day 0’ values). (** All 23 day data represent 2 mice/group). (<b>B</b>) Results are the optical density of the shared proteasome subunit α7, standard proteasome subunits β1 and β5, and immunoproteasome subunits LMP2 (β1i) and LMP7 (β5i), and are the mean ± S.E. of 3–22** mice/group compared to control (day 0). (*, p≤0.05 by one-way ANOVA with Dunnett’s post-test compared to the ‘day 0’ values). (** All 36 day data represent 2 mice/group).</p

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