Application of the
Method of Molecular Voronoi–Dirichlet
Polyhedra for Analysis of Noncovalent Interactions in Crystal Structures
of Flufenamic AcidThe Current Record-Holder of the Number
of Structurally Studied Polymorphs
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Abstract
Crystal
chemical analysis of eight polymorphs of flufenamic acid
(FFA, C<sub>14</sub>H<sub>10</sub>NO<sub>2</sub>F<sub>3</sub>)the
current record-holder of the number of structurally characterized
polymorphic modificationswas carried out using the method
of molecular Voronoi–Dirichlet polyhedra. It was proved that
every polymorph of FFA, as every polymorph of the previous record-holder
ROY (C<sub>12</sub>H<sub>9</sub>N<sub>3</sub>O<sub>2</sub>S), has
a unique set of types of intra- and intermolecular noncovalent interactions
