Spleen cells of <i>Lrrk2</i> (-/-) (“KO”) mice immunized with IRBP secrete lower levels of IFN-γand IL-17 than their WT controls.

Abstract

<p><b>A and C.</b> Levels of IFN-γ and IL-17 measured by ELISA in supernatants of spleen cells of five individual experiments, collected 14 days following immunization and cultured with IRBP at 10 μg/ml for 48 hrs. <b>B and D</b>. Summaries of the averaged and normalized data of the two cytokines in the five individual experiments, as detailed in the Materials and Methods section.</p