InsB<sub>9–23</sub>/IFA immunization temporarily controls recurrent autoimmunity in NOD mice.

Abstract

<p>A, diabetic NOD mice were transplanted with islets from NOD donors (syngeneic) and treated with insB<sub>9–23</sub>/IFA or PBS/IFA. Percentage of islet graft survival after transplantation is shown. B, correlation between blood glucose levels at the time of transplant and the number of days of syngeneic islet engraftment for all mice. Each symbol represents one mouse. Survival curves were compared with the log-rank test. Correlation was done with Pearson coefficient. <i>P</i> values and R<sup>2</sup> values are indicated in the graphs.</p

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