Iron-Catalyzed Intramolecular C(<i>sp</i>²)–N Cyclization of 1‑(<i>N</i>‑Arylpyrrol-2-yl)ethanone <i>O</i>‑Acetyl Oximes toward Pyrrolo[1,2‑<i>a</i>]quinoxaline Derivatives

Abstract

An efficient and convenient iron-catalyzed protocol has been developed for the synthesis of substituted pyrrolo­[1,2-<i>a</i>]­quinoxalines from 1-(<i>N</i>-arylpyrrol-2-yl)­ethanone <i>O</i>-acetyl oximes through N–O bond cleavage and intramolecular directed C–H arylation reactions in acetic acid