<i>Saccharomyces cerevisiae</i> gDNA (BY4741) fragmented with nanodroplets in an ultrasonic bath was comparable in quality to DNA fragmented using a commercial method.
<p><b>(A)</b> Agilent D1000 ScreenTape system traces for DNA samples in microTUBES with the rod (left panel) or microTUBES with nanodroplets (right panel) that were subjected to sequencing. Average size is indicated in base pairs (bp). DNA size markers are denoted by Upper and Lower. <b>(B)</b> Traces showing similar size distribution of DNA after sequencing library preparation. Average size is indicated in base pairs (bp). DNA size markers are denoted by Upper and Lower. <b>(C)</b> Mapping sequencing reads to the <i>Saccharomyces cerevisiae</i> (S288c) reference genome is comparable in detection of single nucleotide variations, insertions, and deletions. Abundance and profile of relative errors in sequencing reads does not indicate a difference in the presence of error bias in the data.</p
