<p>(A) Groups of BALB/c mice (n = 5) were injected s.c. in the right hind leg with 1 × 10<sup>6</sup> transduced tumor cells. Ten days after tumor cell implantation, mice were challenged by s.c. injection with 5×10<sup>5</sup> mock-transduced CT26 cells in the left hind leg. Tumor volume (length × width × height × 0.5) was estimated every 3 or 4 days after challenge. Independent experiments were repeated three times. (B) Tumor free survival rate was estimated simultaneously (n = 20). The tumor free survival rate of respective group is about 40% (CT26/GM-CSF/IL-18), 25% (CT26/GM-CSF), 15% (CT26), and less than 5% (CT26/IL-18 and PBS control)</p
