<p>(A) Spin echo images of the sample. A large voxel of 18 × 18 × 18 mm<sup>3</sup> is marked by a green dashed rectangle, and a small voxel of 6 × 6 × 6 mm<sup>3</sup> is marked by a red dashed rectangle. (B) Conventional 1D non-localized spectrum and the expanded region for metabolites. (C) Conventional 2D <i>J</i>PRESS spectrum after a clockwise rotation of 45° and its projection along the F2 axis acquired from the small voxel after the field shimming procedure. (D) Conventional 2D <i>J</i>PRESS spectrum after a clockwise rotation of 45° and its projection along the F2 axis acquired from the large voxel without the field shimming procedure. (E) 2D localized iDQC<i>J</i>RES spectrum and its 1D <i>J</i>-decoupled projection along the F3 axis acquired from the large voxel without the field shimming procedure.</p
