Facile Synthesis of 3‑<i>N</i>‑Alkyl
Pyrimidin-2,4-diones from <i>N</i>‑Sulfonyloxy Maleimides
and Amines
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Abstract
Reaction
of variously substituted <i>N</i>-trifluoromethanesulfonyloxy
maleimides with primary amines in the presence of potassium carbonate
in DMF at room temperature results in the formation of 3-<i>N</i>-alkyl pyrimidin-2,4-diones in good yield