Enantioselective 6-<i>exo</i>-Bromoaminocyclization of Homoallylic <i>N</i>‑Tosylcarbamates Catalyzed by a Novel Monophosphine-Sc(OTf)₃ Complex

Abstract

A highly enantioselective 6-<i>exo</i>-bromoaminocyclization of (<i>E</i>)-homoallylic <i>N</i>-tosylcarbamates catalyzed by a novel monophosphine-Sc­(OTf)₃ complex is described, giving a wide variety of optically active oxazinanones with high enantioselectivities