Additional file 7: Figure S5. of Morphological change of CD4+ T cell during contact with DC modulates T-cell activation by accumulation of F-actin in the immunology synapse
The distribution of microtubules in CD4+ T cells which made contact with DCs. The distribution of microtubules was measured in an elongated-flattened CD4+ T cell (top line) or a round-flattened CD4+ T cell (middle line). In the presence of the nocodazole, the distribution of microtubules was measured in a CD4+ T cell (bottom line). TCR (red) and ICAM-1 (green) are used to mark the structure of IS, respectively. Dotted white line depicts the contact boundary of CD4+ T cells and DCs. Scale bar is 2Â Îźm
