<p>Synthetic fibrils composed of rVλ6Wil (A), Jto (B), JtoR68S (C), and non-amyloid fibrils elastin (D) were shown to be fibrillar by using electron microscopy (left panels; bar = 100 nm; arrows indicate the region of fibrils shown inset). MTT reduction was measured in cultured AC10 human cardiomyocytes in the presence of fibrils (light) and monomeric proteins (dark) from 1 nM– 1 μM. *<i>p</i><0.05, for an unpaired t-test (right panel, n = 3). EM images were modified equivalently by increasing contrast and applying a shadowing effect, using Image J.</p
