<p>Analyses were performed using DIANA microT v5.0 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140111#pone.0140111.ref036" target="_blank">36</a>] for miR-125b-3p and miR-222-3p and Custom Target Scan v5.2 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0140111#pone.0140111.ref037" target="_blank">37</a>] for chr19_26739-5p. The interaction between 3’UTR of ESR1 and the seed region of miR-222-3p of one binding site is described in the box.</p