Polystyrene
Nanofiber Materials for Visible-Light-Driven
Dual Antibacterial Action via Simultaneous Photogeneration of NO and
O<sub>2</sub>(<sup>1</sup>Δ<sub>g</sub>)
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Abstract
This contribution reports on the
preparation, characterization,
and biological evaluation of electrospun polystyrene nanofiber materials
engineered with a covalently grafted NO photodonor and ionically entangled
tetracationic porphyrin and phthalocyanine photosensitizers. These
photofunctional materials exhibit an effective and simultaneous photogeneration
of two antibacterial species such as nitric oxide (NO) and singlet
oxygen, O<sub>2</sub>(<sup>1</sup>Δ<sub>g</sub>) under illumination
with visible light, as demonstrated by their direct detection using
amperometric and time-resolved spectroscopic techniques. Dual-mode
photoantibacterial action is demonstrated by antibacterial tests carried
out on Escherichia coli