Additional file 3: Figure S2. of A novel aspirin prodrug inhibits NFκB activity and breast cancer stem cell properties

Abstract

GTCpFE inhibits cytokine-induced NFκB target gene expression in breast cancer cells. MCF-7 cells were pretreated for 2 hours with increasing concentrations of GTCpFE followed by treatment with IL-1β (10 ng/ml) for another 2 hours. Expression of NFκB target genes, ICAM1 and CCL2 was measured by RT-QPCR. Drug inhibitory activity is plotted as % of IL-1β alone. (PPTX 72 kb