Targeted HaploSeq generates a single (complete) haplotype structure across MHC/KIR locus. The performance metric of the Targeted HaploSeq protocol, measured by completeness (span of the haplotype bloc), resolution (fraction of het. alleles resolved), and accuracy. While each of these metrics were defined after performing read-based as well as population based haplotyping, seed resolution is estimated only based on read-based haplotyping. The overall resolution is defined as the weighted average among all alleles accross the MHC and KIR loci together. We observe over 50Â % decrease in error rate from 2.3 to 1.06Â % after correcting for potential incorrect local haplotypes from parent-trio data. (TIFF 8219 kb
