Palladium Catalyzed C–I and Vicinal C–H
Dual Activation of Diaryliodonium Salts for Diarylation: Synthesis
of 4,5-Benzocoumarins
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Abstract
With a strategy that
makes use of palladium activation of both
C–I and vicinal C–H bonds of diaryliodonium salts, an
unprecedented approach in diarylation of coumarins was reported. As
such, a wide range of 4,5-benzocoumarins with potential fluorescence
properties have been synthesized in good yields. A series of experiments
suggested that the formation of two carbon–carbon bonds proceeded
in a synergetic manner