Polybacterial infection enhances atherogenic potential of infected ApoE<sup>-/-</sup> mice.

Abstract

<p>(A). Total serum cholesterol and total serum triglycerides are significantly elevated in infected mice. (B). Chylomicrons and VLDL are significantly elevated in infected mice. (C). Acute inflammatory marker SAA is not significantly elevated in infected mice. (D). Oxidized LDL is significantly elevated in infected mice. (E). Serum nitric oxide is significantly decreased in infected mice. Chol—cholesterol, Trigly—triglycerides, CM—chylomicrons, VLDL—very low-density lipoprotein, LDL—low density lipoprotein, HDL—high density lipoprotein, Cn—control, Ply—poly infection, <i>Pg</i>–<i>P</i>. <i>gingivalis</i> infection, <i>Td</i>–<i>T</i>. <i>denticola infection</i>, <i>Tf</i>–<i>T</i>. <i>forsythia</i> infection, <i>Fn</i>–<i>F</i>. <i>nucleatum</i> infection, OxyLDL—oxidized LDL. n = 6, * p < 0.05, ** p < 0.01.</p

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