Long-Lived Nuclear Singlet
Order in Near-Equivalent <sup>13</sup>C Spin Pairs
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Abstract
Molecules that support <sup>13</sup>C singlet states
with lifetimes
of over 10 min in solution have been designed and synthesized. The <sup>13</sup>C<sub>2</sub> spin pairs in the asymmetric alkyne derivatives
are close to magnetic equivalence, so the <sup>13</sup>C long-lived
singlet states are stable in high magnetic field and do not require
maintenance by a radiofrequency spin-locking field. We suggest a model
of singlet relaxation by fluctuating chemical shift anisotropy tensors
combined with leakage associated with slightly broken magnetic equivalence.
Theoretical estimates of singlet relaxation rates are compared with
experimental values. Relaxation due to antisymmetric shielding tensor
components is significant