Copper-Catalyzed Oxidative Homo- and Cross-Coupling
of Grignard Reagents Using Diaziridinone
- Publication date
- Publisher
Abstract
Transition-metal-catalyzed cross-coupling reactions are among the
most powerful synthetic transformations. This paper describes an efficient
copper-catalyzed homo- and cross-coupling of Grignard reagents with
di-<i>tert</i>-butyldiaziridinone as oxidant under mild
conditions, giving the coupling products in good to excellent yields.
The reaction process has a broad substrate scope and is also effective
for the C(sp)–C(sp<sup>3</sup>) coupling
