Photostable Copper Nanoclusters: Compatible Förster
Resonance Energy-Transfer Assays and a Nanothermometer
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Abstract
To address the concern of material
chemists over the issue of stability
and photoluminescent (PL) characteristics of Cu nanoclusters (NCs),
herein we present an efficient protocol discussing PL Cu NCs (Cu/HSA)
having blue emission and high photostability. These PL NCs were illustrated
as efficient probes for Förster resonance energy transfer (FRET)
with a compatible fluorophore (Coumarin 153). Our spectroscopic results
were well complemented by our molecular docking calculations, which
also favored our proposed mechanism for Cu NC formation. The beneficial
aspect and uniqueness of these nontoxic Cu/HSA NCs highlights their
temperature-dependent PL reversibility as well as the reversible FRET
with Coumarin 153, which enables them to be used as a nanothermometer
and a PL marker for sensitive biological samples