Expression of the FBXO32 substrates calcineurin A and IkB-Îą in FDC and IDC. Immunoblot analysis showing calcineurin A and IkB-Îą protein expression in control hearts, in the heart of patients IV.5 and IV.7 carrying the FBXO32 variant, in a cardiomyopathic heart from another family (FDC2) and in idiopathic dilated hearts (IDC). FBXO32 and GAPDH are also shown. (TIF 3699Â kb