Odds-ratio plot and Tartan plot for visualization of statistical associations.

Abstract

<p><b>A</b> Odds-ratio plot, based on an alignment of region of HIV-1 gp120 around the V3 loop (C296-C331). Here, the feature is the predicted co-receptor tropism of HIV-1 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0146409#pone.0146409.ref017" target="_blank">17</a>] (R5 vs. X4 tropic). Bar heights and colors indicate logarithms of odds ratios and negative logarithms of <i>p</i> values, respectively. A reference sequence and sequence positions can be added in the top and bottom rows for orientation. <b>B</b> Tartan plot for the synopsis of two alignment pair association measures, here: −log <i>p</i> from association test between alignment position pairs (upper right triangle) vs. Direct Information between these pairs (lower left triangle). Association strengths are color coded (color legend on the right). For orientation, axes can be annotated and sequence substructures can be indicated by lines.</p

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