Additional file 3: Figure S2. of An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites
(A) Monitorization of the CD34+CD38− primitive phenotype in human-derived CD34+ progenitors co-cultured with hMSCs for 5 and 12 days in the different β-TCP/matrix hybrids. On the left data presented is a mean ± SD of three independent experiments; on the right, dot plots of one representative experiment are shown. (B) Representative SEM images CD34+ HSPCs co-cultured for 12 days in 800-μm β-TCP scaffolds in the presence of hMSC-containing collagen I/III matrix. CD34+ HSPCs (red arrows) are seen in close contact to hMSCs (white arrows) within the scaffold macropores. β-TCP scaffolds (asterisks) were reinforced with collagen I/III (green arrows)
