Additional file 1: Figure S1. The direction of the allelic effect for each of three pleiotropic SNPs in the 12q24.12 region. Figure S2. Protein-protein interactions among three genes in the 12q24.12 region. Table S1. Frequency distribution of minor allele frequencies in Exome chip data. Table S2. Descriptive information of study subjects. Table S3. Replication results of known lipid-associated loci in Korean individuals. Table S4. Population diversity of three pleiotropic SNPs in the 12q24.12 region. Table S5. Evaluation of pleiotropic effect of 12q24.12 (ALDH2, rs671) genotypes. Table S6. Protein-protein interactions among three genes in 12q24.12 region.